ALDH3A1-IN-4

Overview

ALDH3A1-IN-4 is a selective ALDH3A1 inhibitor with an IC 50 of 0.2 μM. ALDH3A1-IN-4 binds to the aldehyde-binding pocket of ALDH3A1 via hydrophobic interactions and van der Waals forces. ALDH3A1-IN-4 acts as a chemosensitizer that sensitizes ALDH3A1-expressing cancer cells to the antiproliferative effect of mafosfamide, but does not produce a sensitizing effect on non-cancer cells that do not express ALDH3A1 . ALDH3A1-IN-4 is applicable to research related to lung adenocarcinoma and glioblastoma.

Application

Products | Products > Disease Areas > Glioma | Products > Disease Areas > Lung Adenocarcinoma | Products > Disease Areas > Glioblastoma | Products > Disease Areas > Cancer | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Respiratory Disease | Products > Disease Areas > Lung Cancer | Products > Disease Areas > Respiratory Cancer | Products > Disease Areas > CNS Neoplasm | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Neurological Disease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Aldehyde Dehydrogenase (ALDH)

Product Information

• Catalog No.: HY-128299
• CAS No.: 324777-01-7
• Molecular Formula: C14H11FN2O2S
• Molecular Weight: 290.31
• Purity: 99.91%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (8.61 mM); Clear solution
• Availability: In-stock

Source

Original product source