MK2-IN-1 hydrochloride

Overview

MK2-IN-1 hydrochloride (compound 1) is a potent and selecitve MAPKAPK2 (MK2) inhibitor with an IC 50 of 0.11 uM for MK2 and an EC 50 of 0.35 uM for pHSP27. MK2-IN-1 hydrochloride impaires the phosphorylation level of serine residues in the Tfcp2l1 protein.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > MAPKAPK2 (MK2) | Products > Signaling Pathways > HSP

Product Information

• Catalog No.: HY-12834A
• CAS No.: 1314118-94-9
• Molecular Formula: C27H26Cl2N4O2
• Molecular Weight: 509.43
• Purity: 98.24%
• Storage: 4°C, stored under nitrogen * In solvent : -80°C, 2 years; -20°C, 1 year (stored under nitrogen)
• Solubility: ≥ 1.67 mg/mL (3.28 mM); Clear solution
• Availability: In-stock

Source

Original product source