RO5454948

Overview

RO5454948 (Compound 9) is the inhibitor for Dyrk1B and Dyrk1A with IC 50 of 68 nM and 22 nM. RO5454948 exhibits cytotoxicity in cancer cell SW620 with EC 50 of 1.9 μM.

Application

Products | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Cancer | Products > Disease Areas > Lipid Metabolism | Products > Disease Areas > Obesity | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > DYRK

Product Information

• Catalog No.: HY-12838
• CAS No.: 1386979-55-0
• Molecular Formula: C23H17Cl2N5O4
• Molecular Weight: 498.32
• Purity: 99.53%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Availability: In-stock

Source

Original product source