Lisaftoclax

Overview

Lisaftoclax (compound 6) is a dual Bcl-2 and Bcl-xl inhibitor with anti-tumor activity, extracted from patent WO2018027097A1. Lisaftoclax exhibits IC 50 values of 2 nM and 5.9 nM for Bcl-2 and Bcl-xl , respectively.

Application

Products | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Bcl-2 Family

Product Information

• Catalog No.: HY-129179
• CAS No.: 2180923-05-9
• Molecular Formula: C45H48ClN7O8S
• Molecular Weight: 882.42
• Purity: 99.78%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: 2.5 mg/mL (2.83 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source