BIIB-028 is an orally active inhibitor for heat shock protein 90 ( Hsp90 ) . BIIB-028 targets the ATP-binding site of Hsp90 , disrupts the function of Hsp90 , leads to the degradation of client proteins, that are crucial for cancer cell survival and proliferation.
Products | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > HSP
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