NPC-15437

Overview

NPC-15437 is a selective PKC inhibitor with an IC 50 of 19 µM. NPC-15437 competitively inhibits phorbol ester- (K i of 5 µM) and phosphatidylserine-induced (K i of 12 µM) PKC activity. NPC-15437 does not inhibits cAMP-dependent or calcium/calmodulin-dependent protein kinases. NPC-15437 augments TRAIL-induced cell death in non-small cell lung cancer and medulloblastoma cells. NPC-15437 can be used for the research of non-small cell lung cancer , medulloblastoma, and neurological disease .

Application

Products | Products > Research Areas > Neurological Disease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy

Product Information

• Catalog No.: HY-129980A
• CAS No.: 136449-85-9
• Molecular Formula: C25H50N4O2
• Molecular Weight: 438.70
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source