Integrin-IN-2 (compound 39) is an orally bioavailable pan αv integrin inhibitor. Integrin-IN-2 can increases the αvβ6 , αvβ3 , αvβ5 and αvβ8 binding affinities with pIC 50 values of 7.8, 8.4, 8.4 and 7.4, respectively.
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