RepSox

RepSox
  • CAS No.:446859-33-2
  • Grade:99.92%
  • Formula:C17H13N5
  • M.W.:287.32
  • Solvent:≥ 7.5 mg/mL (26.10 mM); Clear solution

Overview

RepSox (E-616452) is a potent and selective transforming growth factor-beta receptor I/activin like kinase 5 (TGF-β-RI/ALK5) inhibitor. RepSox inhibits ALK5 autophosphorylation with an IC 50 value of 4 nM. RepSox can be used for the research of obesity and associated metabolic diseases such as type 2 diabetes.

Application

Products | Products > Disease Areas > Urogenital Disease | Products > Disease Areas > Lipid Metabolism | Products > Disease Areas > Pulmonary Disease | Products > Disease Areas > Colorectal Cancer | Products > Disease Areas > Digestive System Cancer | Products > Disease Areas > Prostate Cancer | Products > Disease Areas > Urogenital Cancer | Products > Disease Areas > Pancreatic Cancer | Products > Disease Areas > Glucose Metabolism | Products > Disease Areas > Obesity | Products > Disease Areas > Lung Fibrosis | Products > Disease Areas > Cancer | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Respiratory Disease | Products > Disease Areas > Digestive System Disease | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > TGF-beta/Smad | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > Organoid | Products > Signaling Pathways > TGF-β Receptor

Product Information

  • Catalog No.: HY-13012
  • CAS No.: 446859-33-2
  • Molecular Formula: C17H13N5
  • Molecular Weight: 287.32
  • Purity: 99.92%
  • Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
  • Solubility: ≥ 7.5 mg/mL (26.10 mM); Clear solution
  • Availability: In-stock

Source

Original product source


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