SIS3

Overview

SIS3 is a potent and selective inhibitor of Smad3 with an IC 50 of 3 μM for Smad3 phosphorylation. SIS3 inhibits the myofibroblast differentiation of fibroblasts by TGF-β1 .

Application

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Product Information

• Catalog No.: HY-13013
• CAS No.: 521984-48-5
• Molecular Formula: C28H28ClN3O3
• Molecular Weight: 489.99
• Purity: 99.62%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 2 years; -20°C, 1 year (sealed storage, away from moisture)
• Solubility: 2.5 mg/mL (5.10 mM); Clear solution; Need ultrasonic
• Availability: In-stock

Source

Original product source