DS18561882

Overview

DS18561882 is a highly potent, isozyme-selective methylenetetrahydrofolate dehydrogenase 2 (MTHFD2) inhibitor with an IC 50 value of 0.0063 μM. DS18561882 also has inhibitory effect on MTHFD1 ( IC 50 =0.57 μM). DS18561882 exhibits a good oral pharmacokinetic profile.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Methylenetetrahydrofolate Dehydrogenase (MTHFD)

Product Information

• Catalog No.: HY-130251
• CAS No.: 2227149-22-4
• Molecular Formula: C28H31F3N4O6S
• Molecular Weight: 608.63
• Purity: 99.95%
• Storage: 4°C, stored under nitrogen * In solvent : -80°C, 2 years; -20°C, 1 year (stored under nitrogen)
• Solubility: 2.5 mg/mL (4.11 mM); Clear solution; Need ultrasonic
• Availability: In-stock

Source

Original product source