1-Naphthohydroxamic acid

Overview

1-Naphthohydroxamic acid (Compound 2) is a potent and selective HDAC8 inhibitor with an IC 50 of 14 μM. 1-Naphthohydroxamic acid is more selectively for HDAC8 than class I HDAC1 and class II HDAC6 (IC 50 >100 μM). 1-Naphthohydroxamic acid does not increase global histone H4 acetylation and also does not reduce total intracellular HDAC activity.1-Naphthohydroxamic acid can induce tubulin acetylation.

Application

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Product Information

• Catalog No.: HY-130538
• CAS No.: 6953-61-3
• Molecular Formula: C11H9NO2
• Molecular Weight: 187.19
• Purity: 99.59%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Availability: In-stock

Source

Original product source