SP-96

Overview

SP-96 is a highly potent, selective and non-ATP-competitive Aurora B ( IC 50 =0.316 nM) inhibitor and shows >2000 fold selectivity against FLT3 and KIT. SP-96 shows selective growth inhibition in NCI60 screening, incluing MDA-MD-468 ( GI 50 =107 nM). SP-96 can be used for the research of triple negative breast cancer (TNBC).

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Breast Cancer | Products > Disease Areas > Leukemia/Lymphoma/Myeloma | Products > Disease Areas > Blood Disease | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Aurora Kinase

Product Information

• Catalog No.: HY-131339
• CAS No.: 2682114-54-9
• Molecular Formula: C25H20FN7O
• Molecular Weight: 453.47
• Purity: 99.65%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (5.51 mM); Clear solution
• Availability: In-stock

Source

Original product source