KY19382

KY19382
  • CAS No.:2226664-93-1
  • Grade:98.0%
  • Formula:C17H11Cl2N3O2
  • M.W.:360.19

Overview

KY19382 is a potent and orally active dual inhibitor of CXXC5-DVL and GSK3β , with IC 50 s of 19 and 10 nM, respectively. KY19382 activates Wnt/β-catenin signaling through inhibitory effects on both CXXC5-DVL interaction and GSK3β activity. KY19382 can be used for the research of high fat diet (HFD) induced metabolic diseases.

Application

Products | Products > Disease Areas > Respiratory Disease | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Lipid Metabolism | Products > Disease Areas > Pulmonary Disease | Products > Disease Areas > Breast Cancer | Products > Disease Areas > Pancreatic Cancer | Products > Disease Areas > Digestive System Cancer | Products > Disease Areas > Depression | Products > Disease Areas > Alzheimer's Disease | Products > Disease Areas > Obesity | Products > Disease Areas > Lung Fibrosis | Products > Disease Areas > Cancer | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > Stem Cell/Wnt | Products > Research Areas > Metabolic Disease | Products > Signaling Pathways > GSK-3 | Products > Signaling Pathways > Wnt | Products > Signaling Pathways > β-catenin

Product Information

  • Catalog No.: HY-131447
  • CAS No.: 2226664-93-1
  • Molecular Formula: C17H11Cl2N3O2
  • Molecular Weight: 360.19
  • Purity: 98.0%
  • Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
  • Availability: In-stock

Source

Original product source


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