SR-717

Overview

SR-717 is a non-nucleotide STING agonist with EC 50 s of 2.1 μM and 2.2 μM in ISG-THP1 (WT) and ISG-THP1 cGAS KO (cGAS KO) cell lines, respectively. SR-717 is a stable cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) mimetic. Antitumor activity.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Signaling Pathways > STING

Product Information

• Catalog No.: HY-131454
• CAS No.: 2375421-09-1
• Molecular Formula: C15H8F2LiN5O3
• Molecular Weight: 351.19
• Purity: 99.79%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 2 years; -20°C, 1 year (sealed storage, away from moisture)
• Solubility: ≥ 1 mg/mL (2.85 mM); Clear solution
• Availability: In-stock

Source

Original product source