PF-06843195

Overview

PF-06843195 is a highly selective PI3Kα inhibitor with an IC 50 of 18 nM in Rat1 fibroblasts. The K i s of PF-06843195 for PI3Kα and PI3Kδ in biochemical kinase assay are less than 0.018 nM and 0.28 nM, respectively. PF-06843195 has great suppression of the PI3K/mTOR signaling pathway and durable antitumor efficacy.

Application

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Product Information

• Catalog No.: HY-131972
• CAS No.: 2067281-51-8
• Molecular Formula: C20H25F3N8O4
• Molecular Weight: 498.46
• Purity: 98.12%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.08 mg/mL (4.17 mM); Clear solution
• Availability: In-stock

Source

Original product source