GL0388

Overview

GL0388 is a Bax activator that results in Bax insertion into mitochondrial membrane. GL0388 shows antiproliferative activities against various cancer cells, with IC 50 s of 0.299-1.57 μM. GL0388 activates Bax and induce Bax-mediated apoptosis . GL0388 suppresses breast cancer xenograft tumor growth in vivo.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Breast Cancer | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Bcl-2 Family

Product Information

• Catalog No.: HY-132173
• CAS No.: 2886772-68-3
• Molecular Formula: C21H17FN2O
• Molecular Weight: 332.37
• Purity: 99.22%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (7.52 mM); Clear solution
• Availability: In-stock

Source

Original product source