RET-IN-4

Overview

RET-IN-4 is a potent, selective and orally active RET inhibitor with IC 50 s of 1.29 nM, 1.97 nM, and 0.99 nM for RET (WT) , RET (V804M) , and RET (M918T) , respectively. RET-IN-4 exhibits better kinases selectivity against JAK2 (IC 50 of 4.4 nM) and FLT3 (IC 50 of 30.8 nM). RET-IN-4 has anticancer effects.

Application

Products | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > RET

Product Information

• Catalog No.: HY-132193
• CAS No.: 2436473-55-9
• Molecular Formula: C27H31FN10O2
• Molecular Weight: 546.60
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source