CBP/p300-IN-12

Overview

CBP/p300-IN-12 is a potent and selective covalent histone acetyltransferases p300 ( IC 50 of 166 nM) and CBP inhibitor. CBP/p300-IN-12 decreases the levels of H3K27Ac of PC-3 cells (EC 50 of 37 nM). CBP/p300-IN-12 forms a covalent adduct with C1450.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Epigenetic Reader Domain | Products > Signaling Pathways > Histone Acetyltransferase

Product Information

• Catalog No.: HY-132197
• CAS No.: 2738688-57-6
• Molecular Formula: C33H29F4N5O6
• Molecular Weight: 667.61
• Purity: 99.72%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: 2.08 mg/mL (3.12 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source