Apitolisib

Overview

Apitolisib (GDC-0980; GNE 390; RG 7422) is a selective, potent, orally bioavailable Class I PI3 kinase and mTOR kinase ( TORC1 / 2 ) inhibitor with IC 50 s of 5 nM/27 nM/7 nM/14 nM for PI3Kα/PI3Kβ/PI3Kδ/PI3Kγ , and with a? K i ?of 17 nM for mTOR .

Application

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Product Information

• Catalog No.: HY-13246
• CAS No.: 1032754-93-0
• Molecular Formula: C23H30N8O3S
• Molecular Weight: 498.60
• Purity: 99.29%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 1.43 mg/mL (2.87 mM); Clear solution
• Availability: In-stock

Source

Original product source