MG-132 (GMP)

Overview

MG-132 (GMP) (Z-Leu-Leu-Leu-al (GMP)) is MG-132 ( HY-13259 ) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. MG-132 (Z-Leu-Leu-Leu-al) is a potent proteasome and calpain inhibitor with IC 50 s of 100 nM and 1.2 μM, respectively. MG-132 effectively blocks the proteolytic activity of the 26S proteasome complex. MG-132 , a peptide aldehyde, also is an autophagy activator. MG-132 also induces apoptosis .

Application

Products | Products > GMP Small Molecules | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > Proteasome | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-13259G
• CAS No.: 133407-82-6
• Molecular Formula: C26H41N3O5
• Molecular Weight: 475.62
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source