PYZD-4409

Overview

PYZD-4409 is a specific inhibitor of the ubiquitin-activating enzyme UBA1 with an IC 50 of 20 μM (cell-free enzymatic assay). PYZD-4409 induces cell death in malignant cells and preferentially inhibits the clonogenic growth of primary acute myeloid leukemia cells.

Application

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Product Information

• Catalog No.: HY-13297
• CAS No.: 423148-78-1
• Molecular Formula: C14H7ClFN3O5
• Molecular Weight: 351.67
• Purity: 98.0%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.5 mg/mL (7.11 mM); Clear solution
• Availability: In-stock

Source

Original product source