TrxR-IN-2

Overview

TrxR-IN-2 is a thioredoxin reductase ( TrxR ) inhibitor. TrxR-IN-2 increases reactive oxidative species ( ROS ) levels and decreases mitochondrial transmembrane potential levels. TrxR-IN-2 triggers DNA damage via H2AX regulation, and induces autophagy via LC3 , beclin-1 , and p62 regulation. TrxR-IN-2 can be used for the research of drug-resistant hepatocellular carcinoma [1] .

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Liver Cancer | Products > Disease Areas > Digestive System Cancer | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Autophagy | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Drug Resistance | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Beclin1 | Products > Signaling Pathways > p62 | Products > Signaling Pathways > TrxR | Products > Signaling Pathways > Reactive Oxygen Species (ROS) | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > Atg8/LC3

Product Information

• Catalog No.: HY-132972
• CAS No.: 2866261-50-7
• Molecular Formula: C22H22N4O4
• Molecular Weight: 406.43
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source