BAY-985

Overview

BAY-985, a chemical probe, is a highly potent, orally active and selective ATP-competitive dual inhibitor of TBK1 and IKKε with IC 50 s of 2/30 and 2 nM for TBK1 (low/high ATP) and IKKε , respectively. Antitumor efficacy.

Application

Products | Products > Signaling Pathways > NF-κB | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Signaling Pathways > IKK

Product Information

• Catalog No.: HY-133117
• CAS No.: 2409479-29-2
• Molecular Formula: C27H30F3N9O
• Molecular Weight: 553.58
• Purity: 99.69%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.08 mg/mL (3.76 mM); Clear solution
• Availability: In-stock

Source

Original product source