FM26

Overview

FM26 (compound 25) is a potent and allosteric retinoic acid receptor-related orphan receptor γt (RORγt) inverse agonists with an IC 50 of 264 nM. FM26 has a distinct isoxazole chemotype and effectively reduces IL-17a mRNA production in EL4 cells.

Application

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Product Information

• Catalog No.: HY-133128
• CAS No.: 2407981-35-3
• Molecular Formula: C22H15ClF3N3O3
• Molecular Weight: 461.82
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source