RORγt Inverse agonist 10

Overview

RORγt Inverse agonist 10 is a potent and orally bioavailable RORγt (retinoic acid receptor-related orphan nuclear receptor gamma t) inverse agonist, with an IC 50 of 51 nM. RORγt is a major transcription factor of genes related to psoriasis pathogenesis such as IL-17A , IL-22 , and IL-23R

Application

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Product Information

• Catalog No.: HY-133552
• CAS No.: 2413986-35-1
• Molecular Formula: C25H26F6N6O3
• Molecular Weight: 572.50
• Purity: 99.13%
• Storage: 4°C, sealed storage, away from moisture and light * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
• Solubility: ≥ 10 mg/mL (17.47 mM); Clear solution
• Availability: In-stock

Source

Original product source