Monoethyl phthalate

Overview

Monoethyl phthalate is an orally active PDX-1 activator and the major hydrolytic metabolite of Diethyl phthalate ( HY-Y0284 ) in vivo, with reproductive toxicity. Monoethyl phthalate targets aromatase ( aromatase/CYP19A1 ) and PPAR to induce cell proliferation. The plasma protein binding rate of Monoethyl phthalate in rats and humans is lower than that of Diethyl phthalate . It exhibits significant enterohepatic circulation in rats and mainly accumulates in liver tissues. Monoethyl phthalate shows no estrogenic activity in estrogen-dependent human breast cancer cells. Monoethyl phthalate can be used in studies of reproductive toxicity and related environmental endocrine disruption mechanisms.

Application

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Product Information

• Catalog No.: HY-133668
• CAS No.: 2306-33-4
• Molecular Formula: C10H10O4
• Molecular Weight: 194.19
• Purity: 98.58%
• Storage: Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (12.87 mM); Clear solution
• Availability: In-stock

Source

Original product source