(R)-Benpyrine

(R)-Benpyrine
  • CAS No.:2637243-08-2
  • Grade:99.08%
  • Formula:C16H16N6O
  • M.W.:308.34

Overview

(R)-Benpyrine is the isomer of Benpyrine ( HY-133807 ), and can be used as an experimental control. Benpyrine is a highly specific and orally active TNF-α inhibitor with a K D value of 82.1 μM. Benpyrine tightly binds to TNF-α and blocks its interaction with TNFR1, with an IC 50 value of 0.109 μM. Benpyrine has the potential for TNF-α mediated inflammatory and autoimmune disease research .

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Cancer | Products > Disease Areas > Pain | Products > Disease Areas > Autoimmune Disease | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > TNF Receptor

Product Information

  • Catalog No.: HY-133807B
  • CAS No.: 2637243-08-2
  • Molecular Formula: C16H16N6O
  • Molecular Weight: 308.34
  • Purity: 99.08%
  • Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
  • Availability: In-stock

Source

Original product source


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