AP-1/NF-κB activation inhibitor 1

Overview

AP-1/NF-κB activation inhibitor 1 is a potent AP-1 and NF-κB mediated transcriptional activation inhibitor ( IC 50 =1 μM), without blocking basal transcription driven by the β-actin promoter. AP-1/NF-κB activation inhibitor 1 has a similar inhibitory effect on the production of IL-2 and IL-8 levels in stimulated cells.

Application

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Product Information

• Catalog No.: HY-133987
• CAS No.: 188936-12-1
• Molecular Formula: C13H11F3N4O4
• Molecular Weight: 344.25
• Purity: 98.08%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.08 mg/mL (6.04 mM); Clear solution
• Availability: In-stock

Source

Original product source