SIRT-IN-3

Overview

SIRT-IN-3 is a potent SIRT inhibitor, with an IC 50 of 17 μM for SIRT1 . SIRT-IN-3 shows about 4-fold and 14-fold selectivity for SIRT1 over SIRT2 and SIRT3 , respectively (IC 50 of 74 μM and 235 μM for SIRT2 and SIRT3 , respectively).

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Cancer | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Digestive System Inflammation | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Signaling Pathways > Sirtuin

Product Information

• Catalog No.: HY-133998
• CAS No.: 1211-19-4
• Molecular Formula: C13H12N2O
• Molecular Weight: 212.25
• Purity: 98.10%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 2.08 mg/mL (9.80 mM); Clear solution
• Availability: In-stock

Source

Original product source