PF-5274857 hydrochloride

Overview

PF-5274857 hydrochloride is a potent, selective, orally active and brain-penetrant antagonist of Smo , with an IC 50 of 5.8 nM and K i of 4.6 nM. PF-5274857 hydrochloride has potential for research of tumor types including brain tumors and brain metastasis driven by an activated Hh pathway.

Application

Products | Products > Signaling Pathways > Stem Cell/Wnt | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Signaling Pathways > Smo

Product Information

• Catalog No.: HY-13459A
• CAS No.: 1613439-62-5
• Molecular Formula: C20H26Cl2N4O3S
• Molecular Weight: 473.42
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source