MRTX849 analog 24

Overview

MRTX849 analog 24 is a KRAS G12C inhibitor with a human IC 50 of 140 nM. MRTX849 analog 24 binds to KRAS G12C , forms a covalent interaction, and acts as a click probe to bait the protein target in proteomic studies. MRTX849 analog 24 exhibits cellular activity in cancer cells. MRTX849 analog 24 can be used for the research of kras G12C -mutant cancer .

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Ras

Product Information

• Catalog No.: HY-134654
• CAS No.: 2490716-96-4
• Molecular Formula: C36H39ClFN7O2
• Molecular Weight: 656.19
• Purity: 98.01%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source