YM-341619

Overview

YM-341619 (AS1617612) is a potent and orally active STAT6 inhibitor with an IC 50 of 0.70 nM. YM-341619 inhibits Th2 differentiation in mouse spleen T cells induced by IL-4 ( IC 50 =0.28 nM) without affecting Th1 cell differentiation. YM-341619 is a promising compound for the the research of allergic diseases, such as allergic asthma.

Application

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Product Information

• Catalog No.: HY-134771
• CAS No.: 643082-52-4
• Molecular Formula: C22H21F3N6O2
• Molecular Weight: 458.44
• Purity: 98.01%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: 2.5 mg/mL (5.45 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source