(1S,2S)-ML-SI3

Overview

(1S,2S)-ML-SI3 is a trans-isomer of ML-SI3 that targets all three isoforms of TRPML . (1S,2S)-ML-SI3 is an activator of TRPML2 and TRPML3 ( EC 50 =2.7 μM/10.8 μM) and a potent inhibitor of TRPML1 ( IC 50 =5.9 μM).

Application

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Product Information

• Catalog No.: HY-134819
• CAS No.: 2563870-87-9
• Molecular Formula: C23H31N3O3S
• Molecular Weight: 429.58
• Purity: 99.96%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 2.5 mg/mL (5.82 mM); Clear solution
• Availability: In-stock

Source

Original product source