(32-Carbonyl)-RMC-5552

Overview

(32-Carbonyl)-RMC-5552 is a potent mTOR inhibitor . (32-Carbonyl)-RMC-5552 inhibits mTORC1 and mTORC2 substrate (p-P70S6K-(T389), p-4E-BP1-(T37/36), AND p-AKT1/2/3-(S473)) phosphorylation with pIC 50 s of > 9, >9 and between 8 and 9, respectively (patent WO2019212990A1, example 2).

Application

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Product Information

• Catalog No.: HY-134903
• CAS No.: 2382768-55-8
• Molecular Formula: C93H134N10O24
• Molecular Weight: 1776.11
• Purity: 95.41%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: 5.5 mg/mL (3.10 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source