LW106

Overview

LW106 is a selective IDO1 inhibitor with an IC 50 of 1.57 μM. LW106 has no inhibitory effect on IDO2 and TDO. LW106 inhibits tumor outgrowth by limiting stroma-immune crosstalk and CSC enrichment in the tumor microenvironment. LW106 reduces subpopulation of cancer stem cells (CSCs) in xenografted tumors in which less proliferative/invasive tumor cells and more tumor cells apoptosis . LW106 can be used for the studies of lung cancer and melanoma.

Application

Products | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > Indoleamine 2,3-Dioxygenase (IDO) | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > SWI/SNF Complex

Product Information

• Catalog No.: HY-134920
• CAS No.: 2116519-76-5
• Molecular Formula: C11H11N5O2
• Molecular Weight: 245.24
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source