J14

J14
  • CAS No.:1043854-13-2
  • Grade:99.91%
  • Formula:C28H25ClN4O2S
  • M.W.:517.04
  • Solvent:≥ 2.17 mg/mL (4.20 mM); Clear solution

Overview

J14 is a reversible sulfiredoxin inhibitor with an IC 50 of 8.1 μM. J14 induces oxidative stress (intracellular ROS accumulation) by inhibiting sulfiredoxin , leading to cytotoxicity and cancer cell death.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Cancer | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Parkinson's Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Reactive Oxygen Species (ROS)

Product Information

  • Catalog No.: HY-135008
  • CAS No.: 1043854-13-2
  • Molecular Formula: C28H25ClN4O2S
  • Molecular Weight: 517.04
  • Purity: 99.91%
  • Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
  • Solubility: ≥ 2.17 mg/mL (4.20 mM); Clear solution
  • Availability: In-stock

Source

Original product source


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