Antiproliferative agent-54

Overview

Antiproliferative agent-54 (Compound 6z) is the inhibitor for multiple kinases, such as ABL WT , B-RAF , EGFR , HCK , LYN A and SRC with IC 50 of 6-50 nM. Antiproliferative agent-54 inhibits proliferation of several cancer cell, inhibits HUVEC and HepG2, with EC 50 of 34 and 38 nM. Antiproliferative agent-54 exhibits good pharmacokinetic characteristics in rats.

Application

Products | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > JAK/STAT Signaling | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Signaling Pathways > Src | Products > Signaling Pathways > VEGFR | Products > Signaling Pathways > Raf | Products > Signaling Pathways > EGFR

Product Information

• Catalog No.: HY-135216
• CAS No.: 1240322-54-6
• Molecular Formula: C29H25F3N6O3
• Molecular Weight: 562.54
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source