DB1976

Overview

DB1976 is a selenophene analog of DB270 and a potent and cell-permeable fully efficacious transcription factor PU.1 inhibitor. DB1976 potently inhibits PU.1 binding ( IC 50 of 10 nM) and strongly inhibits the PU.1/DNA complex (with high DB1976-λB affinity, K D of 12 nM) in vitro. DB1976 has apoptosis -inducing effect.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-135797
• CAS No.: 1557397-51-9
• Molecular Formula: C20H16N8Se
• Molecular Weight: 447.35
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source