Estramustine phosphate sodium, an estradiol analog, is an orally active antimicrotubule chemotherapy agent. Estramustine phosphate sodium depolymerises microtubules by binding to microtubule associated proteins (MAPs) and/or to tubulin . Estramustine phosphate sodium can interfere mitosis , trigger cell death and induce apoptosis , which can be used for the research of cancer like prostate cancer .
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