PHD-1-IN-1

Overview

PHD-1-IN-1 is an orally active and potent HIF prolylhydroxylase domain-1 (PHD-1) inhibitor with an IC 50 of 0.034 μM. PHD-1-IN-1 has a unique monodentate binding interaction with the active site Fe 2+ ion and induces the formation of an "Arg367-out" pocket.

Application

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Product Information

• Catalog No.: HY-136300
• CAS No.: 2009343-14-8
• Molecular Formula: C13H8N4
• Molecular Weight: 220.23
• Purity: 99.21%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 9.75 mg/mL (44.27 mM); Clear solution
• Availability: In-stock

Source

Original product source