Rogaratinib

Overview

Rogaratinib (BAY1163877) is a potent and selective fibroblast growth factor receptor ( FGFR ) inhibitor. Rogaratinib inhibits FGFRs with IC50s of 11.2 nM (FGFR1), <1 nM (FGFR2), 18.5 nM (FGFR3), 127 nM (VEGFR3/FLT4), 201 nM (FGFR4), respectively.

Application

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Product Information

• Catalog No.: HY-100019
• CAS No.: 1443530-05-9
• Molecular Formula: C23H26N6O3S
• Molecular Weight: 466.56
• Purity: 99.86%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 0.56 mg/mL (1.20 mM); Clear solution
• Availability: In-stock

Source

Original product source