AZ13824374

Overview

AZ13824374 is a potent and selective ATAD2 bromodomain inhibitor ( pIC 50 of 6.9 in HCT116 cells). AZ13824374 disrupts chromatin interactions and gene transcription by binding to the acetyl-lysine binding site of the ATAD2 bromodomain. AZ13824374 has anticancer activity against breast cancer .

Application

Products | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Epigenetic Reader Domain

Product Information

• Catalog No.: HY-136521
• CAS No.: 3040082-19-4
• Molecular Formula: C30H39FN8O2
• Molecular Weight: 562.68
• Purity: 99.22%
• Storage: 4°C, sealed storage, away from moisture and light * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
• Solubility: ≥ 5 mg/mL (8.89 mM); Clear solution
• Availability: In-stock

Source

Original product source