DSR-141562

Overview

DSR-141562 is a novel, orally active, and selective brain-penetrant phosphodiesterase 1 ( PDE1 ) inhibitor. DSR-141562 shows preferential selectivity for human PDE1B with an IC 50 of 43.9 nM, and the IC 50 values for human PDE1A and 1C are 97.6 and 431.8 nM, respectively. DSR-141562 can be used for the study of positive symptoms, negative symptoms and cognitive impairments associated with schizophrenia.

Application

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Product Information

• Catalog No.: HY-136569
• CAS No.: 2007975-22-4
• Molecular Formula: C19H25F3N4O3
• Molecular Weight: 414.42
• Purity: 99.87%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (6.03 mM); Clear solution
• Availability: In-stock

Source

Original product source