BRD4 degrader-3

Overview

BRD4 degrader-3 is a potent bromodomain BRD4 degrader extracted from patent WO2020055976A1, example 1a, has IC 50 s of 15.5 and 12.3 nM for BRD4-BD1 and BRD4-BD2, respectively. PROTAC BRD4 Degrader-7 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

Application

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Product Information

• Catalog No.: HY-136857
• CAS No.: 2413382-30-4
• Molecular Formula: C26H29N5O2S
• Molecular Weight: 475.61
• Purity: 98.41%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (5.26 mM); Clear solution
• Availability: In-stock

Source

Original product source