Nimustine

Overview

Nimustine is an alkylating agent, which induces DNA double-strand breaks (DSBs) and inter-strand crosslinks (ICLs), thereby activating the DNA damage response (DDR) signaling pathway. Nimustine activates p38 MAPK/JNK signaling pathway, and exhibits antitumor activity.

Application

Products | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > JNK | Products > Signaling Pathways > AP-1 | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > DNA Alkylator/Crosslinker | Products > Signaling Pathways > DNA/RNA Synthesis | Products > Signaling Pathways > p38 MAPK

Product Information

• Catalog No.: HY-13703
• CAS No.: 42471-28-3
• Molecular Formula: C9H13ClN6O2
• Molecular Weight: 272.69
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source