Nimustine hydrochloride

Overview

Nimustine hydrochloride (ACNU) is the hydrochloride salt form of Nimustine ( HY-13703 ). Nimustine hydrochloride is an alkylating agent, which induces DNA double-strand breaks (DSBs) and inter-strand crosslinks (ICLs), thereby activating the DNA damage response (DDR) signaling pathway. Nimustine hydrochloride activates p38 MAPK/JNK signaling pathway, and exhibits antitumor activity.

Application

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Product Information

• Catalog No.: HY-13703A
• CAS No.: 55661-38-6
• Molecular Formula: C9H14Cl2N6O2
• Molecular Weight: 309.15
• Purity: 99.00%
• Storage: 4°C, sealed storage, away from moisture and light * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
• Solubility: ≥ 2.08 mg/mL (6.73 mM); Clear solution
• Availability: In-stock

Source

Original product source