Ingenol 3,20-dibenzoate

Overview

Ingenol 3,20-dibenzoate is a potent protein kinase C ( PKC ) isoform-selective agonist. Ingenol 3,20-dibenzoate induces selective translocation of nPKC-delta, -epsilon, and -theta and PKC-mu from the cytosolic fraction to the particulate fraction and induces morphologically typical apoptosis through de novo synthesis of macromolecules. Ingenol 3,20-dibenzoate increases the IFN-γ production and degranulation by NK cells, especially when NK cells are stimulated by NSCLC cells.

Application

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Product Information

• Catalog No.: HY-137295
• CAS No.: 59086-90-7
• Molecular Formula: C34H36O7
• Molecular Weight: 556.65
• Purity: 99.16%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 5 mg/mL (8.98 mM); Clear solution
• Availability: In-stock

Source

Original product source