Venadaparib

Overview

Venadaparib (IDX-1197) is a potent, selective and orally active PARP inhibitor with IC 50 s of 1.4 nM and 1.0 nM for PARP1 and PARP2 , respectively. Venadaparib does not sensitive to PARP-5. Venadaparib prevents the repair of DNA single-strand breaks (SSB) and can be used for solid tumors research.

Application

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Product Information

• Catalog No.: HY-137457
• CAS No.: 1681017-83-3
• Molecular Formula: C23H23FN4O2
• Molecular Weight: 406.45
• Purity: 98.52%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 5.75 mg/mL (14.15 mM); Clear solution
• Availability: In-stock

Source

Original product source