Vevorisertib trihydrochloride

Overview

Vevorisertib (ARQ 751) trihydrochloride is a selective, allosteric, pan- AKT and AKT1-E17K mutant inhibitors. Vevorisertib trihydrochloride potently inhibit phosphorylation of AKT . Vevorisertib trihydrochloride has Kd values of 1.2 nM and 8.6 nM for AKT1 and AKT1-E17K, respectively. Vevorisertib trihydrochloride has IC 50 values of 0.55, 0.81, and 1.3 nM for AKT1 , AKT2 , and AKT3 , respectively. Vevorisertib trihydrochloride can be used for the research of cancer .

Application

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Product Information

• Catalog No.: HY-137458A
• CAS No.: 1416775-08-0
• Molecular Formula: C35H41Cl3N8O
• Molecular Weight: 696.11
• Purity: 98.05%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 5.25 mg/mL (7.54 mM); Clear solution
• Availability: In-stock

Source

Original product source