O6BTG-C8-αGlu

Overview

O6BTG-C8-αGlu is an O6-methylguanine-DNA methyltransferase ( MGMT ) inhibitor with an IC 50 of 0.45 μM. At a concentration of 0.1 μM, O6BTG-C8-αGlu can completely inhibit MGMT in HeLaS3 cells. Even when applied chronically at high doses (up to 20 μM), it does not exhibit cytotoxicity. O6BTG-C8-αGlu is suitable for research on MGMT -related cancer diseases.

Application

Products | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > DNA Methyltransferase

Product Information

• Catalog No.: HY-13786
• CAS No.: 793035-88-8
• Molecular Formula: C24H34BrN5O7S
• Molecular Weight: 616.53
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source